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Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

Maria Frank-Kamenetsky, Xiaoyan M Zhang, Steve Bottega, Oivin Guicherit, Hynek Wichterle, Henryk Dudek, David Bumcrot, Frank Y Wang, Simon Jones, Janine Shulok, Lee L Rubin and Jeffery A Porter*

Journal of Biology 2002, 1:10 doi:10.1186/1475-4924-1-10

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