Journal of Biology
Volume 2
Issue 2 |
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 MinireviewOf mice and men: phylogenetic footprinting aids the discovery of regulatory elementsZhaolei Zhang and Mark Gerstein  Department of Molecular Biophysics and Biochemistry, Yale University, 266 Whitney Avenue, New Haven, CT 06520-8114, USA  author email corresponding author email
Journal of Biology 2003,
2:11doi:10.1186/1475-4924-2-11 Abstract
Phylogenetic footprinting is an approach to finding functionally important sequences in the genome that relies on detecting their high degrees of conservation across different species. A new study shows how much it improves the prediction of gene-regulatory elements in the human genome. | 
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