|
The reference collection of 14 gene pairs and 40 verified transcription-factor-binding sites used for testing |
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| Gene name |
Human sequence |
Rodent sequence |
Transcription factors |
Binding sequence |
Location |
MEDLINE ID [49] |
|
|
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| Skeletal muscle actin |
AF182035* |
M12347 |
SP1 |
GCGGGGTGGCGCG
|
-64/-51 |
11017083 |
| SRF |
ACCCAAATATGGCT
|
-100/ -86 |
1922033 |
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| TEF-1 |
GACATTCCTGCG
|
-73/-51 |
11017083 |
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| Aldolase A α B crystallin |
X12447* |
J05517 |
MEF2 |
CCTAAATATAGGTC
|
-125/-111 |
8413246 |
| M28638* |
U04320 |
SP1 |
AGGAGGAGGGGCA
|
-343/-330 |
11017083 |
|
| SRF |
GCCCAAGATAGTTG
|
-393/-379 |
11017083 |
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| Cardiac α myosin heavy chain |
Z20656 |
U71441 and M62404* |
MEF2 |
TTAAAAATAACTGA
|
-327/-313 |
8366095 |
| TEF-1 |
AGGAGGAATGTGC
|
-239/-226 |
7961957 |
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| SRF |
CTCCAAATTTAGGC
|
-62/-48 |
8782063 |
|||
| CEBPα |
U34070* |
M62362 |
AP2 α |
GGCCGGGGGCGGA
|
-243/-232 |
9520389 |
| TBP |
TATAAAA
|
-30/-24 |
96003748 |
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| Cell division cycle protein 2 |
L06298 and |
U69555 |
E2F |
TCTTTCGCGC
|
-131/-119 |
94094909 |
| X66172* |
cETS |
GGGAAG
|
-109/-104 |
951721551 |
||
| Cholesterol 7 α hydroxylase |
L13460 |
U01962* |
HNF3 β |
TCTGTTTGTTCT
|
-175/-166 |
9799805 |
| cEBP |
ATGTTATGTCA
|
-227/-217 |
28182075 |
|||
| Early growth response protein 1 |
AJ243425 |
M22326* |
SRF |
TGCTTCCCATATATGGCCATGT
|
-88/-67 |
90097904 |
| SRF |
CCAGCGCCTTATATGGAGTGGC
|
-358/-337 |
90097904 |
|||
| SRF |
GAAACGCCATATAAGGAGCAGG
|
-412/-391 |
90097904 |
|||
| Glucose-6-phosphatase |
AF051355* |
U57552 |
HNF3 β |
CCAAAGA
|
-72/-66 |
9369482 |
| HNF3 β |
ACAAACG
|
-91/-85 |
9369482 |
|||
| HNF3 β |
GTTTTTGAG
|
-82/-74 |
9369482 |
|||
| HNF3 β |
TGTGTGC
|
-180/-174 |
9369482 |
|||
| HNF3 β |
TGTTTGC
|
-139/-133 |
9369482 |
|||
| HNF1 |
AGTTAATCATTGGCC
|
-226/-212 |
9369482 |
|||
| Leptin |
U43589 |
U36238* |
SP1 |
GGGCGG
|
-100/-95 |
9492033 |
| cEBP |
GTTGCGCAAG
|
-58/-49 |
9492033 |
|||
| TBP |
TATAAG
|
-33/-28 |
9492033 |
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| Lipoprotein lipase |
M29549* |
M63335 |
NFY |
CAAT
|
-65/-61 |
1918010 |
| cEBP |
TAGCCAAT
|
-68/-61 |
1918010 |
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| TBP |
TATAA
|
-27/-23 |
1918010 |
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| Muscle creatine kinase |
M21487 |
AF188002 and M21390* |
SRF |
CCATGTAAGG
|
-1236/-1227 |
93233638 |
| AP2 α |
GGCCTGGGGA
|
-1220/-1211 |
93233638 |
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| MEF2 |
TCTAAAAATAAC
|
-1078/-1067 |
93233638 |
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| MYF |
GGGCCAGCTGTCCC
|
-253/-240 |
96347575 |
|||
| MYF |
CCAACACCTGCTGC
|
-1157/-1144 |
96347575 |
|||
| P53 |
ATACAAGGCC
|
-176/-167 |
96047120 |
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| P53 |
ATACAAGGCC
|
-158/-149 |
96047120 |
|||
| Rb susceptibility gene |
L11910* |
M86180 U49920 and S66110 |
SP1 |
GGGCGG
|
-202/-188 |
1881452 |
| Troponin I |
L21905* |
MEF2 |
AGACTATAATAGCC
|
-976/-962 |
9774679 |
|
| MYF |
TAAACAGGTGCAGC
|
-879/-865 |
9774679 |
|||
|
GenBank accession numbers [41] are given for the human and rodent sequences. The transcription-factor-binding sequences refer to the human or rodent sequence(s) marked with an asterisk. 'Location' refers to the position of the TFBS relative to the transcription start site. | ||||||
Lenhard et al. Journal of Biology 2003 2:13 doi:10.1186/1475-4924-2-13 |
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