Shrinkage control: regulation of insulin-mediated growth by FOXO transcription factors

doi:10.1186/1475-4924-2-18

Journal of Biology

Volume 2
Issue 3

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Shrinkage control: regulation of insulin-mediated growth by FOXO transcription factors

Thomas P Neufeld

Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455, USA

author email corresponding author email

Journal of Biology 2003, 2:18doi:10.1186/1475-4924-2-18


Published:	11 September 2003

Abstract

The insulin signaling pathway regulates organismal growth in response to nutrient conditions by controlling a range of metabolic and biosynthetic processes. Recent studies in Drosophila have shown how transcriptional responses to reduced insulin and nutrient levels can act to inhibit growth.