The Drosophila Forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling
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* Corresponding author: Ernst Hafen hafen@zool.unizh.ch
Journal of Biology 2003, 2:20 doi:10.1186/1475-4924-2-20
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Method
Olivier Elemento, Saeed Tavazoie Genome Biology 2005, 6:R18 (26 January 2005) The authors describe a powerful approach for discovering globally conserved regulatory elements between two genomes that does not require alignments. Its application to pairs of yeasts, worm, flies and mammals, yields a large number of known and novel putative regulatory elements, many of which show surprising conservation across large phylogenetic distances. |
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Minireview
Shrinkage control: regulation of insulin-mediated growth by FOXO transcription factors Thomas P Neufeld Journal of Biology 2003, 2:18 (11 September 2003) |
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Research news
Controlling how many cells make a fly Pete Moore Journal of Biology 2003, 2:16 (21 August 2003) |