Table 2 |
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|
RNAi screen results classified by annotated phenotype |
|||||
| Genes identified* |
|||||
|
|
|||||
| Phenotypic class† |
Total |
Total S2R+ |
Total Kc167 |
Both‡ |
|
|
|
|||||
| Cell shape |
105 |
93 |
32 |
20 |
|
| F-actin organization |
94 |
74 |
50 |
30 |
|
| Microtubule organization |
71 |
48 |
37 |
14 |
|
| Decreased cell density |
66 |
62 |
8 |
4 |
|
| Cell size |
48 |
25 |
33 |
10 |
|
| DNA morphology |
27 |
17 |
22 |
12 |
|
| Cell viability |
6 |
3 |
4 |
1 |
|
| Total phenotypes |
417 |
322 (77%) |
186 (44%) |
91 (22%) |
|
| Total genes |
160 |
146 (91%) |
79 (49%) |
65 (41%) |
|
|
*The number of genes categorized with a specific RNAi phenotype in duplicate screens. †The major classes of RNAi phenotypes. Individual genes with multiple phenotypes were counted within each of the phenotypic classes scored. ‡Genes identified by a defect assigned to the same phenotypic class in both cell types. | |||||
Kiger et al. Journal of Biology 2003 2:27 doi:10.1186/1475-4924-2-27 |
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