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Connecting LKB1 and AMPK links metabolism with cancer

Pete Moore

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Journal of Biology 2003, 2:24  doi:10.1186/1475-4924-2-24

Published: 29 October 2003

Abstract

The tumor suppressor gene product LKB1 has been identified as the upstream activating kinase for the stress-responsive AMP-activated kinase, providing a link between regulators of cellular metabolism and cell proliferation in cancer.