A functional genomic analysis of cell morphology using RNA interference
-
* Corresponding author: N Perrimon perrimon@rascal.med.harvard.edu
Journal of Biology 2003, 2:27 doi:10.1186/1475-4924-2-27
Accesses
- Last 30 days: 176 accesses
- Last year: 2108 accesses
- All time: 54656 accesses
Cited by
BioMed Central: 16 citations
|
Research article
Hua Bai, Fang Zhu, Kapil Shah, Subba Palli BMC Genomics 2011, 12:388 (1 August 2011) |
|
Review
Rosangela Sozzani, Philip N Benfey Genome Biology 2011, 12:219 (28 March 2011) A review of new methods for high-throughput phenotyping of multicellular organisms.
|
|
Research article
Li Wang, Zhidong Tu, Fengzhu Sun BMC Genomics 2009, 10:220 (12 May 2009) |
|
Research
Tao Liu, David Sims, Buzz Baum Genome Biology 2009, 10:R26 (5 March 2009) Parallel RNA interference screens and gene expression arrays in six Drosophila cell lines identified regulators of cell morphology, including a neuronal function for the kinase minibrain/DYRK1A in the regulation of protrusion morphology. |
|
Research
PDGF/VEGF signaling controls cell size in Drosophila David Sims, Peter Duchek, Buzz Baum Genome Biology 2009, 10:R20 (12 February 2009) Pvr and its ligands, Pvf 2 and 3, which are upstream of Ras and PI3kinase, are identified from a genome-wide screen in Drosophila cells, as regulators of cell growth. |
|
Method
Ramanuj DasGupta, Kent Nybakken, Matthew Booker, Bernard Mathey-Prevot, Foster Gonsalves, Binita Changkakoty, Norbert Perrimon Genome Biology 2007, 8:R203 (28 September 2007) A second generation dsRNA library was used to re-assess factors that influence the outcome of transcriptional reporter-based whole-genome RNAi screens for the Wnt/Wingless (wg) and Hedgehog (hh)-signaling pathways. |
|
Editorial
Journal of Biology celebrates its fifth anniversary Journal of Biology 2007, 6:5 (29 June 2007) |
|
Software
CellProfiler: image analysis software for identifying and quantifying cell phenotypes Anne E Carpenter, Thouis R Jones, Michael R Lamprecht, Colin Clarke, In Kang, Ola Friman, David A Guertin, Joo Chang, Robert A Lindquist, Jason Moffat, Polina Golland, David M Sabatini Genome Biology 2006, 7:R100 (31 October 2006) CellProfiler, the first free, open-source system for flexible and high-throughput cell image analysis is described. |
|
Minireview
Transcriptional control of dendritic patterning in Drosophila neurons Michel Tassetto, Fen-Biao Gao Genome Biology 2006, 7:225 (28 July 2006) An RNA interference screen reveals roles for transcription factors in regulating the outgrowth and branching of the dendrites of |
|
Software
Analysis of cell-based RNAi screens Michael Boutros, Lígia P Brás, Wolfgang Huber Genome Biology 2006, 7:R66 (25 July 2006) cellHTS is a new method for the analysis and documentation of RNAi screens. |
|
Minireview
RNA interference pinpoints regulators of cell size and the cell cycle Megan J Cully, Sally J Leevers Genome Biology 2006, 7:219 (30 May 2006) A genome-wide RNA interference screen in |
|
Research article
Inclusion of Scar/WAVE3 in a similar complex to Scar/WAVE1 and 2 Craig F Stovold, Thomas H Millard, Laura M Machesky BMC Cell Biology 2005, 6:11 (7 March 2005) The similar protein-protein interactions and cellular localizations of the three Scar/WAVE proteins suggest that they participate similarly in regulating actin assembly and that any differences are due to varied tissue expression or affinities for binding partners.
|
|
Methodology article
Functional complementation of RNA interference mutants in trypanosomes Filippo Rusconi, Mickaël Durand-Dubief, Philippe Bastin BMC Biotechnology 2005, 5:6 (9 February 2005) Functional complementation experiments in Trypanosomes confirm that phenotypic effects observed in RNAi experiments are indeed the result of specific silencing of the targeted gene.
|
|
Minireview
Peter van Roessel, Andrea H Brand Genome Biology 2004, 5:208 (30 January 2004) A membrane channel, encoded by the gene |
|
Research news
RNAi and the shape of things to come Jonathan B Weitzman Journal of Biology 2003, 2:23 (4 November 2003) |
|
Minireview
Functional genomics of cell morphology using RNA interference: pick your style, broad or deep Thomas D Pollard Journal of Biology 2003, 2:25 (1 October 2003) |