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Bending out and breaking away: host-cell accomplices in retroviral escape

Melvyn W Yap and Jonathan P Stoye*

Author Affiliations

Division of Virology, National Institute for Medical Research, The Ridgeway, London NW7 1AA, UK

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Journal of Biology 2003, 3:3 doi:10.1186/1475-4924-3-3

Published: 19 December 2003

Abstract

Budding through the host-cell membrane is a key step in the life cycle of many viruses. Recent studies of retrovirus replication implicate a large number of cellular proteins in this process.