Wnt signaling and the developmental fate of lung cells
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Journal of Biology 2004, 3:9 doi:10.1186/jbiol9Published: 28 June 2004
Constitutive activation of the Wnt signaling pathway during lung development in mouse embryos causes some cells to develop a gut-like phenotype. These findings are reminiscent of classical embryological experiments and may have therapeutic implications for pre-cancerous metaplasias.