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Wnt signaling and the developmental fate of lung cells

Julie Clayton

Citation and License

Journal of Biology 2004, 3:9  doi:10.1186/jbiol9

Published: 28 June 2004

Abstract

Constitutive activation of the Wnt signaling pathway during lung development in mouse embryos causes some cells to develop a gut-like phenotype. These findings are reminiscent of classical embryological experiments and may have therapeutic implications for pre-cancerous metaplasias.