|
Penetrance of phenotypes in Ptdsr -/- mice from E9.5 to E18.5, as detected by gross morphology |
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| Dysmorphic phenotypes |
Ratio in analyzed mice (affected/total) |
Penetrance (%) |
|
|
||
| Head malformations |
9/198 |
4.5 |
| cleft |
4/198 |
2.0 |
| others |
5/198 |
2.5 |
| Edema (E12.5-E15.5) |
15/155 |
9.7 |
| Pale appearance (= E14.5) |
72/72 |
100 |
| Ocular lesions |
28/198 |
14.1 |
| unilaterally absent eyes |
21/198 |
10.6 |
| right |
16/198 |
8.1 |
| left |
5/198 |
2.5 |
| bilaterally absent eyes |
7/198 |
3.5 |
|
Subsets of the major categories of malformation are indicated by indentation. | ||
Böse et al. Journal of Biology 2004 3:15 doi:10.1186/jbiol10 |
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