Table 1

Penetrance of phenotypes in Ptdsr -/- mice from E9.5 to E18.5, as detected by gross morphology

Dysmorphic phenotypes

Ratio in analyzed mice (affected/total)

Penetrance (%)


Head malformations

9/198

4.5

cleft

4/198

2.0

others

5/198

2.5

Edema (E12.5-E15.5)

15/155

9.7

Pale appearance (= E14.5)

72/72

100

Ocular lesions

28/198

14.1

unilaterally absent eyes

21/198

10.6

right

16/198

8.1

left

5/198

2.5

bilaterally absent eyes

7/198

3.5


Subsets of the major categories of malformation are indicated by indentation.

Böse et al. Journal of Biology 2004 3:15   doi:10.1186/jbiol10

Open Data