All systems GO for understanding mouse gene function

doi:10.1186/jbiol19

Journal of Biology

Volume 3
Issue 5

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All systems GO for understanding mouse gene function

Chris Holmes¹^,2 and Steve DM Brown¹

¹MRC Mammalian Genetics Unit, Harwell OX11 0RD, UK

²Department of Statistics, Oxford Centre for Gene Function, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK

author email corresponding author email

Journal of Biology 2004, 3:20doi:10.1186/jbiol19


Published:	17 December 2004

Abstract

It is widely supposed that the tissue specificity of gene expression indicates gene function. Now, an extensive analysis of gene expression in the mouse reveals that quantitative measurement of expression levels in different tissues can contribute powerfully to the prediction of gene function.