Correspondence between gene expression patterns and GO-BP annotations. (a) Ratios for the 21,622 expressed genes were grouped by two-dimensional hierarchical agglomerative clustering and diagonalization, using the Pearson correlation coefficient. (b) Negative logs of P values resulting from applying the Wilcoxon-Mann-Whitney (WMW) test to each of the GO-BP categories in each of the tissues are shown. The categories (vertical axis) were clustered and ordered as in (a). (c, d) 'Density' of GO-BP annotations significantly enriched in specific points along the vertical axis at left (genes) are indicated; note that genes are in the same order in (a, b, c).
Zhang et al. Journal of Biology 2004 3:21 doi:10.1186/jbiol16