Research news
The GTPase switch in ribosomal translocation
Journal of Biology 2005, 4:7 doi:10.1186/jbiol28
Published: 27 June 2005Abstract
Information from careful measurements of the affinity of ribosome-associated proteins for GTP and GDP, and from structural analyses, suggests that elongation factor-G must assume three different structures during protein synthesis and that the ribosome itself acts as a guanine-nucleotide exchange factor. Is it time to re-write the textbook description of translation?
