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Recycling signals in the neural crest

Lisa A Taneyhill and Marianne Bronner-Fraser*

Author Affiliations

Division of Biology 139-74, California Institute of Technology, Pasadena, CA 91125, USA

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Journal of Biology 2006, 4:10  doi:10.1186/jbiol31

Published: 9 January 2006

Abstract

Vertebrate neural crest cells are multipotent and differentiate into structures that include cartilage and the bones of the face, as well as much of the peripheral nervous system. Understanding how different model vertebrates utilize signaling pathways reiteratively during various stages of neural crest formation and differentiation lends insight into human disorders associated with the neural crest.