Open Access Highly Accessed Research article

Compound developmental eye disorders following inactivation of TGFβ signaling in neural-crest stem cells

Lars M Ittner1,6†, Heiko Wurdak2†, Kerstin Schwerdtfeger1†, Thomas Kunz1, Fabian Ille2, Per Leveen3, Tord A Hjalt4, Ueli Suter2, Stefan Karlsson3, Farhad Hafezi5, Walter Born1 and Lukas Sommer2*

1 Research Laboratory for Calcium Metabolism, Orthopedic University Hospital Balgrist, CH-8008 Zurich, Switzerland

2 Institute of Cell Biology, Department of Biology, ETH-Hönggerberg, CH-8093 Zurich, Switzerland

3 Departments for Molecular Medicine and Gene Therapy, Lund University, S-22184 Lund, Sweden

4 Department of Cell and Molecular, Biology, Section for Cell and Developmental Biology, Lund University, S-22184 Lund, Sweden

5 IROC, Institute for Refractive and Ophthalmic Surgery, CH-8002 Zurich, Switzerland

6 Current address: Brain & Mind Research Institute (BMRI), University of Sydney, NSW 2050, Australia

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Journal of Biology 2005, 4:11 doi:10.1186/jbiol29

Published: 14 December 2005

Additional files

Additional data file 1:

A figure showing the absence of Wnt1 expression during eye formation

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Additional data file 2:

A figure showing the expression of TGFβ isoforms during eye formation

Format: PDF Size: 217KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data