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Compound developmental eye disorders following inactivation of TGFβ signaling in neural-crest stem cells

Lars M Ittner1,6* email, Heiko Wurdak2* email, Kerstin Schwerdtfeger1* email, Thomas Kunz1 email, Fabian Ille2 email, Per Leveen3 email, Tord A Hjalt4 email, Ueli Suter2 email, Stefan Karlsson3 email, Farhad Hafezi5 email, Walter Born1 email and Lukas Sommer2 email

Research Laboratory for Calcium Metabolism, Orthopedic University Hospital Balgrist, CH-8008 Zurich, Switzerland

Institute of Cell Biology, Department of Biology, ETH-Hönggerberg, CH-8093 Zurich, Switzerland

Departments for Molecular Medicine and Gene Therapy, Lund University, S-22184 Lund, Sweden

Department of Cell and Molecular, Biology, Section for Cell and Developmental Biology, Lund University, S-22184 Lund, Sweden

IROC, Institute for Refractive and Ophthalmic Surgery, CH-8002 Zurich, Switzerland

Current address: Brain & Mind Research Institute (BMRI), University of Sydney, NSW 2050, Australia

author email corresponding author email* Contributed equally

Journal of Biology 2005, 4:11doi:10.1186/jbiol29

Published: 14 December 2005

Additional files

Additional data file 1:

A figure showing the absence of Wnt1 expression during eye formation

Format: PDF Size: 182KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional data file 2:

A figure showing the expression of TGFβ isoforms during eye formation

Format: PDF Size: 217KB Download file

This file can be viewed with: Adobe Acrobat Reader


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