Regulators of kinesin involved in polarized trafficking and axon outgrowth

doi:10.1186/jbiol41

Journal of Biology

Volume 5
Issue 4

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Regulators of kinesin involved in polarized trafficking and axon outgrowth

Shuo Luo and Michael L Nonet

Department of Anatomy and Neurobiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis, MO 63110, USA

author email corresponding author email

Journal of Biology 2006, 5:8doi:10.1186/jbiol41


Published:	25 May 2006

Abstract

Proteins such as UNC-76 that associate with kinesin motors are important in directing neurite extension. A small Caenorhabditis elegans coiled-coil protein, UNC-69, has now been shown to interact with UNC-76 and to be involved in axonal (but not dendritic) transport and outgrowth, as well as synapse formation.