Regulators of kinesin involved in polarized trafficking and axon outgrowth
Department of Anatomy and Neurobiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis, MO 63110, USA
Journal of Biology 2006, 5:8 doi:10.1186/jbiol41Published: 25 May 2006
Proteins such as UNC-76 that associate with kinesin motors are important in directing neurite extension. A small Caenorhabditis elegans coiled-coil protein, UNC-69, has now been shown to interact with UNC-76 and to be involved in axonal (but not dendritic) transport and outgrowth, as well as synapse formation.