Research article
The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans
- Equal contributors
1 Institute for Molecular Biology, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland
2 Neuroscience Center Zurich, ETH and University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland
3 Program in Genetics, SUNY at Stony Brook, Stony Brook, NY 11794, USA
4 Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
5 Howard Hughes Medical Institute, Department of Molecular, Cellular and Developmental Biology, Sinsheimer Laboratories, University of California, Santa Cruz, CA 95064, USA
6 Biology Department, Muhlenberg College, Allentown, PA 18104, USA
7 Zoological Institute, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland
8 Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
9 Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
10 Current address: Department of Neurosurgery, Brigham and Women's Hospital, Children's Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
11 Current address: Abteilung für Klinische Chemie und Biochemie, Universitäts-Kinderklinik, Steinwiesstrasse 75, CH-8032 Zürich, Switzerland
12 Current address: Clinigen, Inc., 400 W. Cummings Park #5700, Woburn, MA 01801, USA
Journal of Biology 2006, 5:9 doi:10.1186/jbiol39
Published: 25 May 2006Additional files
Additional data file 1:
Supplementary results and tables
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Additional data file 2:
A figure showing that the overexpression of a full-length UNC-69(M1I)::GFP protein rescues locomotion defects of the unc-69(e587) mutants
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Additional data file 3:
A figure showing the extent of the ok339 deletion
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Additional data file 4:
A figure showing that RNAi knockdown of chicken UNC-69/SCOCO results in epaxial nerve pathfinding defects
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