Table 2

Axon outgrowth and guidance defects of HSN, DD/VD, ALA and AVK neurons

Axon guidance phenotype

Defect in unc-69(e587) mutants (%)

n


HSN

Ventral outgrowth

16

70

Midline crossover (HSNL)

38

40

Failure to reach nerve ring

99

59

DD/VD

Dorsal outgrowth

33

45

ALA

Premature termination

67

30

AVKR

Premature termination or crossover

85

20


The morphology of HSN neurons was visualized using antibodies against serotonin; that of DD/VD neurons using antibodies against GABA; and that of ALA and AVKR neurons using antibodies against FMRF-amide. See Materials and methods for details. n, number of animals scored.

Su et al. Journal of Biology 2006 5:9   doi:10.1186/jbiol39

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