Imaging with isotopes: high resolution and quantitation

First paragraph (this article has no abstract)

"By the help of Microscopes, there is nothing so small as to escape our inquiry; hence there is a new visible World discovered to the understanding." Thus wrote Robert Hooke in his pioneering work Micrographia [1] published by the Royal Society in 1664. In this revolutionary book, Hooke described with excitement his discoveries using a simple light microscope, coining the word 'cell' to define the microscopic structures he saw in cork and plant samples. In this issue of Journal of Biology [2], Claude Lechene and colleagues describe a 21st century microscopy technology (Figure 1) that also reveals images we have never seen before.