Imaging with isotopes: high resolution and quantitation
Journal of Biology 2006, 5:17 doi:10.1186/jbiol48Published: 5 October 2006
First paragraph (this article has no abstract)
"By the help of Microscopes, there is nothing so small as to escape our inquiry; hence there is a new visible World discovered to the understanding." Thus wrote Robert Hooke in his pioneering work Micrographia  published by the Royal Society in 1664. In this revolutionary book, Hooke described with excitement his discoveries using a simple light microscope, coining the word 'cell' to define the microscopic structures he saw in cork and plant samples. In this issue of Journal of Biology , Claude Lechene and colleagues describe a 21st century microscopy technology (Figure 1) that also reveals images we have never seen before.