High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry

Claude Lechene¹ , Francois Hillion² , Greg McMahon¹ , Douglas Benson³ , Alan M Kleinfeld⁴ , J Patrick Kampf⁴ , Daniel Distel⁵ , Yvette Luyten⁵ , Joseph Bonventre⁶ , Dirk Hentschel⁶ , Kwon Moo Park⁶ , Susumu Ito⁷ , Martin Schwartz⁸ , Gilles Benichou⁹ and Georges Slodzian¹⁰

¹  National Resource for Imaging Mass Spectrometry, Harvard Medical School and Department of Medicine, Brigham and Women's Hospital, Cambridge, MA 02139, USA

²  Cameca, 29 Quai des Gresillons, 92622 Gennevilliers Cedex, France

³  NSee Inc., 106 Greenhaven Lane, Cary, NC 27511, USA

⁴  Torrey Pines Institute for Molecular Studies, San Diego, CA 92121, USA

⁵  Ocean Genome Legacy Foundation, Ipswich, MA 01938, USA

⁶  Harvard Medical School and Renal Division, Brigham and Women's Hospital, Boston, MA 02115, USA

⁷  Harvard Medical School, Boston, MA 02115, USA

⁸  Department of Microbiology, University of Virginia, Charlottesville, VA 22908, USA

⁹  Harvard Medical School and Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA

¹⁰  Universite Paris-Sud, Centre de Spectrométrie Nucléaire et de Spectrométrie de Masse, 91406 Orsay, France