Minireview
Multilevel regulation of growth rate in yeast revealed using systems biology
Author affiliations
The Broad Institute of Harvard & MIT, Chemical Biology Program, 7 Cambridge Center, Cambridge, MA 02142, USA
Citation and License
Journal of Biology 2007, 6:3 doi:10.1186/jbiol56
Published: 30 April 2007Abstract
The effect of changing growth rates on the transcriptome, proteome and metabolome has been systematically studied. Measurements made under varying nutrient conditions, corresponding to biochemical pathways that correlate primarily with growth rate, reveal a central role for mitochondrial metabolism and the TOR (target of rapamycin) signaling pathway.
