Open Access Highly Accessed Research article

Growth control of the eukaryote cell: a systems biology study in yeast

Juan I Castrillo1, Leo A Zeef1, David C Hoyle2, Nianshu Zhang1, Andrew Hayes1, David CJ Gardner1, Michael J Cornell13, June Petty1, Luke Hakes1, Leanne Wardleworth1, Bharat Rash1, Marie Brown4, Warwick B Dunn6, David Broadhurst46, Kerry O'Donoghue5, Svenja S Hester5, Tom PJ Dunkley5, Sarah R Hart4, Neil Swainston6, Peter Li6, Simon J Gaskell46, Norman W Paton36, Kathryn S Lilley5, Douglas B Kell46 and Stephen G Oliver16*

Author Affiliations

1 Faculty of Life Sciences, Michael Smith Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK

2 Northwest Institute for Bio-Health Informatics (NIBHI), School of Medicine, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK

3 School of Computer Science, Kilburn Building, University of Manchester, Oxford Road, Manchester M13 9PL, UK

4 School of Chemistry, Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess St, Manchester M1 7DN, UK

5 Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Downing Site, Cambridge CB2 1QW, UK

6 Manchester Centre for Integrative Systems Biology, Manchester Interdisciplinary Biocentre, University of Manchester, 131 Princess St, Manchester M1 7DN, UK

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Journal of Biology 2007, 6:4  doi:10.1186/jbiol54

Published: 30 April 2007

Additional files

Additional data file 1:

Supplementary figures S1-S28.

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Additional data file 2:

Supplementary tables S1-S30.

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Additional data file 3:

Legends to supplementary figures and tables

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Additional data file 4:

Supplementary methods.

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Additional data file 5:

Additional studies on transcriptional control of cell growth.

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Additional data file 6:

Proteome-transcriptome correlations.

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Additional data file 7:

Main concepts on translational control efficiency and translational control

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Additional data file 8:

Global patterns of relative changes in translational control efficiencies.

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