Integration of proteome and transcriptome studies. Proteome-transcriptome correlations are determined by the relative changes in protein levels versus relative changes in transcriptional levels from μ = 0.1 to 0.2/h under conditions of carbon limitation. (a) Log2 correlations with the most relevant outliers (cases in which changes in transcript levels do not result in comparable changes at the protein level) named. (b) Correlations between relative changes in natural values. The lines with y/x slope 0.5, 1 and 2 respectively allow to delimit groups of protein/transcript pairs that are correlated (y/x ratio >1) and anti-correlated (y/x ratio <1), and their limits (majority of them with y/x ratios within 0.5 and 2; [0.5 <y/x ratio < 2]).
Castrillo et al. Journal of Biology 2007 6:4 doi:10.1186/jbiol54