Table 4

Genetic interactions within the bar-1 module

Target gene

bar-1-linked (in SGI network)

bar-1-linked (retest)

C27F2.10

Y

Y

efl-1

N

N

lin-2

N

N

lin-7

Y

Y

lin-35

Y

Y

lin-39

N

N

ogt-1

Y

W

prx-5

Y

Y

T20B12.7

Y

Y

ZC395.10

Y

N

bar-1

ND

N

B0432.3

ND

Y

exo-3

ND

N

F29C12.4

ND

Y

F54C9.6

ND

Y

lin-23

ND

N

mrp-5

ND

Y

T01E8.6

ND

Y

T09A5.5

ND

Y

ubc-18

ND

N

Y48E1B.5

ND

Y

The target genes are the 21 genes of the bar-1 module, including the bar-1 query. The second column lists the nine interactions between the targets and the bar-1 query within the bar-1 module that were tested in the original SGI matrix. Y, an interaction was inferred; N, no interaction was inferred; ND, gene pair not tested in SGI. In the retest, all nodes within the bar-1 module were targeted by RNAi in the background of bar-1(gm80). ogt-1 interacted weakly (W) in the direct test, and also had weak interaction scores within the original SGI matrix. We therefore counted ogt-1 as a target that behaved similarly in both the SGI matrix and the detailed examination of the bar-1 module.

Byrne et al. Journal of Biology 2007 6:8   doi:10.1186/jbiol58