Open Access Highly Accessed Research article

Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress

Markus Ralser1*, Mirjam M Wamelink2, Axel Kowald14, Birgit Gerisch1, Gino Heeren3, Eduard A Struys2, Edda Klipp1, Cornelis Jakobs2, Michael Breitenbach3, Hans Lehrach1 and Sylvia Krobitsch1*

Author Affiliations

1 Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany

2 Department of Clinical Chemistry, Metabolic Unit, VU University Medical Center, Amsterdam, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands

3 Department of Cell Biology, University of Salzburg, Hellbrunnerstrasse 34, 5020 Salzburg, Austria

4 Current address: Medical Proteome Center, Ruhr University Bochum, Universitätsstrasse 150, 44801 Bochum, Germany

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Journal of Biology 2007, 6:10  doi:10.1186/jbiol61

Published: 21 December 2007

Additional files

Additional data file 1:

C. elegans experiment.

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Additional data file 2:

A figure and a table of the reactions included in the mathematical model.

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Additional data file 3:

Metabolite concentrations.

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Additional data file 4:

Plasmids and oligonucleotides.

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Additional data file 5:

SBML code for the mathematical model.

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