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Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress

Markus Ralser1 email, Mirjam M Wamelink2 email, Axel Kowald1,4 email, Birgit Gerisch1 email, Gino Heeren3 email, Eduard A Struys2 email, Edda Klipp1 email, Cornelis Jakobs2 email, Michael Breitenbach3 email, Hans Lehrach1 email and Sylvia Krobitsch1 email

1Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany

2Department of Clinical Chemistry, Metabolic Unit, VU University Medical Center, Amsterdam, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands

3Department of Cell Biology, University of Salzburg, Hellbrunnerstrasse 34, 5020 Salzburg, Austria

4Current address: Medical Proteome Center, Ruhr University Bochum, Universitätsstrasse 150, 44801 Bochum, Germany

author email corresponding author email

Journal of Biology 2007, 6:10doi:10.1186/jbiol61

Published: 21 December 2007

Additional files

Additional data file 1:

C. elegans experiment.

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Additional data file 2:

A figure and a table of the reactions included in the mathematical model.

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Additional data file 3:

Metabolite concentrations.

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Additional data file 4:

Plasmids and oligonucleotides.

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Additional data file 5:

SBML code for the mathematical model.

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