Multiplexed detection of proteins in cell lysate using high-density microarrays. (a) Cyclic voltammogram of an individual microelectrode protected with an mPEG protein-inhibiting layer (black line), and following electrochemical desorption of the mPEG monolayer (blue line), and after functionalization with peptide aptamer STMpep2 (orange line). (b) Δφ(ω) of the complex impedance for microelectrodes functionalized with mPEG (black circles), STMpep2 (orange circles) and STMpep9 (blue circles) following exposure to a lysate containing CDK2. (c) As (b) but following exposure to cell lysate containing CDK4.
Evans et al. Journal of Biology 2008 7:3 doi:10.1186/jbiol62