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The future of artemisinins: natural, synthetic or recombinant?

Marcel Hommel

Author affiliations

Institut Pasteur, 25-28 rue du Dr Roux, Paris 75724 Cedex 15, France

Citation and License

Journal of Biology 2008, 7:38  doi:10.1186/jbiol101

Published: 15 December 2008

Abstract

Artemisinins are the most important anti-malarial drugs in use today, but are more costly than previous anti-malarials and production and price tend to fluctuate. Alternative ways of producing artemisinins are discussed here in the light of a recent paper in BMC Biotechnology on improving the yield of the precursor, artemisinic acid, in genetically engineered yeast.