Minireview
A Caenorhabditis elegans genetic-interaction map wiggles into view
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Correspondence: Kristin C Gunsalus kcg1@nyu.edu
Center for Genomics and Systems Biology and Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York, NY 10003, USA
Journal of Biology 2008, 7:8 doi:10.1186/jbiol70
Published: 7 March 2008Abstract
Systematic mapping of genetic-interaction networks will provide an essential foundation for understanding complex genetic disorders, mechanisms of genetic buffering and principles of robustness and evolvability. A recent study of signaling pathways in Caenorhabditis elegans lays the next row of bricks in this foundation.