A Caenorhabditis elegans genetic-interaction map wiggles into view
Center for Genomics and Systems Biology and Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York, NY 10003, USA
Journal of Biology 2008, 7:8 doi:10.1186/jbiol70Published: 7 March 2008
Systematic mapping of genetic-interaction networks will provide an essential foundation for understanding complex genetic disorders, mechanisms of genetic buffering and principles of robustness and evolvability. A recent study of signaling pathways in Caenorhabditis elegans lays the next row of bricks in this foundation.