Email updates

Keep up to date with the latest news and content from Journal of Biology and BioMed Central.

Open Access Highly Accessed Research article

Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system

Ruolan Han1, Yin M Yang1, Joerg Dietrich2, Anne Luebke3, Margot Mayer-Pröschel1 and Mark Noble1*

Author Affiliations

1 Department of Biomedical Genetics and University of Rochester Stem Cell and Regenerative Medicine Institute, University of Rochester Medical Center, Elmwood Avenue, Rochester, NY 14642, USA

2 Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Fruit Street, Wang 835, Boston, MA 02114, USA

3 Department of Neurobiology and Anatomy, University of Rochester Medical Center, Elmwood Avenue, Rochester, NY 14642, USA

For all author emails, please log on.

Journal of Biology 2008, 7:12  doi:10.1186/jbiol69

Published: 22 April 2008

Additional files

Additional data file 1:

A representative confocal micrograph of TUNEL+ cells co-labeled with cell-type-specific markers. (A-A") show a TUNEL+ DCX+ cell in the sub-ventricular zone; (B-B") show a TUNEL+ Olig2+ cell in the CC; (C-C") show a TUNEL+ GFAP+ cell in the CC. The scale bars represent 10 μm

Format: EPS Size: 8.8MB Download file

Open Data