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Spatially patterned gradients of synaptic connectivity are established early in the developing retina
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Correspondence: Susana Cohen-Cory scohenco@uci.edu
Department of Neurobiology and Behavior, University of California, Irvine, 2205 McGaugh Hall, Irvine, CA 92697, USA
Journal of Biology 2008, 7:15 doi:10.1186/jbiol76
Published: 9 June 2008Abstract
Retinal neurons receive input from other cells via synapses and the position of these synapses on the neurons reflects the retinal regions from which information is received. A new study in Neural Development establishes that the spatial distribution of excitatory synaptic inputs emerges at the onset of synapse formation rather than as a result of changes during neuronal reorganisation.