|
Gene expression changes seen in earthworms exposed to five different soil contaminants |
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| Copper |
Cadmium |
Fluoranthene |
Atrazine |
TNT |
|
|
|
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| Species |
L. rubellus |
L. rubellus |
L. rubellus |
L. rubellus |
Eisenia fetida |
| Exposure time |
70 days |
28 days |
28 days |
28 days |
28 days |
| Exposure concentration range (mg/kg) |
10-480 |
13-500 |
14-533 |
19-59 |
2-39 |
| Metabolic category |
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| Detoxification |
Y |
Y |
Y |
Y |
|
| Oxidative stress |
Y |
Y |
Y |
Y |
|
| Mitochondrial electron transport |
Y |
Y |
Y |
Y |
Y |
| Calcium binding and signaling |
Y |
Y |
Y |
||
| Iron homeostasis and oxygen transport |
Y |
Y |
Y |
||
| Blood coagulation and fibrinolysis |
Y |
||||
| Impaired immune function |
Y |
Y |
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| Protein damage repair and catabolism |
Y |
Y |
Y |
||
| Lipid metabolism |
Y |
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| Glycolysis and carbohydrate metabolism |
Y |
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| Cell cycle and apoptosis |
Y |
Y |
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| Muscle contraction |
Y |
Y |
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| DNA damage and repair |
Y |
Y |
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| Neurological dysfunction |
Y |
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| References |
[10] |
[11] |
[11] |
[11] |
[12,13] |
|
Y indicates the broad metabolic categories in which significant changes in gene expression were observed in response to the indicated contaminants. | |||||
van Straalen and Roelofs Journal of Biology 2008 7:19 doi:10.1186/jbiol80 |
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