Table 1

Useful links to therapy, disease, drug and drug-target network data

Name

Description

References

DrugBank

A bioinformatics-cheminformatics resource combining detailed drug data with comprehensive drug target information with over 4,900 drug entries (about 3,500 experimental) and about 1,500 non-redundant protein entries

[26]

Drug-target Network

Network data of 890 drugs and 394 target human proteins

[6]

Drug-Therapy Network

Three layers of drug-therapy networks according to the ATC classification

[8]

Online Mendelian Inheritance in Man (OMIM)

A knowledgebase of human genes and genetic disorders

[27]

Potential Drug Target Database (PDTD)

A three-dimensional drug target structure database with a target identification option

[28]

Predicted drug targets

A set of 1,383 predicted drug targets

[17]

Protein ligand network

A network of 4,208 ligands and about 15,000 binding sites

[9]

Therapeutic Target Database

Lists over 1,500 therapeutic targets, disease conditions and corresponding drugs

[29]

FDA Orange Book

Approved drug products with therapeutic equivalence evaluations

[32]

Investigational Drugs database (IDdb)

Thomson Investigational drugs database including information on 107,000 patents, 25,000 investigational drugs and 80,000 chemical structures

[33]

TDR Targets Database

Identification and ranking targets against neglected tropical diseases

[34]

Spiro et al. Journal of Biology 2008 7:20   doi:10.1186/jbiol81