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Evolution of virulence in malaria

Bridget Penman email and Sunetra Gupta email

Department of Zoology, University of Oxford, South Parks Road, Oxford, OX1 3PS, UK

author email corresponding author email

Journal of Biology 2008, 7:22doi:10.1186/jbiol83

Published: 28 August 2008

Abstract

The pathogenesis of severe malarial disease is not yet fully understood. It is clear that host immunopathology plays a central role, and a recent paper in BMC Evolutionary Biology suggests that the ability of the parasite to stimulate interleukin-10 production is a major factor and speculates on its impact on the coevolution of host and parasite.


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