Journal of Biology
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MinireviewEvolution of virulence in malariaBridget Penman and Sunetra Gupta  Department of Zoology, University of Oxford, South Parks Road, Oxford, OX1 3PS, UK author email corresponding author email
Journal of Biology 2008,
7:22doi:10.1186/jbiol83
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| Published: |
28 August 2008 |
Abstract
The pathogenesis of severe malarial disease is not yet fully understood. It is clear that host immunopathology plays a central role, and a recent paper in BMC Evolutionary Biology suggests that the ability of the parasite to stimulate interleukin-10 production is a major factor and speculates on its impact on the coevolution of host and parasite. |