Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injury

doi:10.1186/jbiol85

Journal of Biology

Volume 7
Issue 7

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Research article

Transplanted astrocytes derived from BMP- or CNTF-treated glial-restricted precursors have opposite effects on recovery and allodynia after spinal cord injury

Jeannette E Davies¹ , Christoph Pröschel² , Ningzhe Zhang² , Mark Noble² , Margot Mayer-Pröschel² and Stephen JA Davies¹

¹Department of Neurosurgery, Anschutz Medical Campus, University of Colorado Denver, 12800 East 19th Ave, Aurora, CO 80045, USA

²Department of Biomedical Genetics, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA

author email corresponding author email

Journal of Biology 2008, 7:24doi:10.1186/jbiol85


Published:	19 September 2008

Additional files

Additional data file 1:

A figure showing that transplanted GRP cells express neurocan and NG2, but suppress host expression of these molecules at 4 days post transplantation to dorsal column injuries.

Format: EPS Size: 13.8MB Download file

Additional data file 2:

A figure showing failure of axons to regenerate across GDACNTF-transplanted injuries.

Format: EPS Size: 19.1MB Download file

Additional data file 3:

A figure showing neuroprotection of injured red nucleus neurons.

Format: EPS Size: 19.8MB Download file