Differential expression of Olig2 protein by different astrocyte populations. (a) GDAsBMP do not express Olig2. (b) In sharp contrast, GDAsCNTF are uniformly immunopositive for Olig2 in vitro. (c) A subset of endogenous GFAP+ astrocytes in the margins of untreated dorsal column spinal cord injuries is also Olig2-immunoreactive. Survival, 8 days post-injury. Note the nuclear localization of Olig2 in GDAsCNTF in vitro and in reactive, endogenous GFAP+ astrocytes in vivo. Scale bars: (a,b) 50 μm; (c) 25 μm.
Davies et al. Journal of Biology 2008 7:24 doi:10.1186/jbiol85