Figure 3.

Differential expression of Olig2 protein by different astrocyte populations. (a) GDAs^BMP do not express Olig2. (b) In sharp contrast, GDAs^CNTF are uniformly immunopositive for Olig2 in vitro. (c) A subset of endogenous GFAP⁺ astrocytes in the margins of untreated dorsal column spinal cord injuries is also Olig2-immunoreactive. Survival, 8 days post-injury. Note the nuclear localization of Olig2 in GDAs^CNTF in vitro and in reactive, endogenous GFAP⁺ astrocytes in vivo. Scale bars: (a,b) 50 μm; (c) 25 μm.