Neuroprotection of red nucleus neurons. Injured left-side red nuclei contained an average of 52% of the neurons counted in uninjured right-side red nuclei at 5 weeks after transection of the right-side rubrospinal tract. The numbers of neurons in the injured left-side red nuclei of GRP- and GDACNTF-transplanted animals were no different from controls, and contained an average of 55% and 51%, respectively, of the neurons counted in the uninjured right-side nuclei. In contrast, the number of neurons in the injured left-side red nuclei of GDABMP-transplanted animals was 81% of the total number of neurons in uninjured right-side nuclei. *p < 0.01. Error bars represent 1 SD.
Davies et al. Journal of Biology 2008 7:24 doi:10.1186/jbiol85