RNA interference in nematodes and the chance that favored Sydney Brenner
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Journal of Biology 2008, 7:34 doi:10.1186/jbiol97Published: 13 November 2008
The efficiency of RNA interference varies between different organisms, even among nematodes. A recent report of successful RNA interference in the nematode Panagrolaimus superbus in BMC Molecular Biology has implications for the comparative study of the functional genomics of nematode species, and prompts reflections on the choice of Caenorhabditis elegans as a model organism.