Life and death as a T lymphocyte: from immune protection to HIV pathogenesis
- Equal contributors
Lymphocyte Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10 Center Dr MSC-1892, Bethesda, MD, USA
Journal of Biology 2009, 8:91 doi:10.1186/jbiol198Published: 27 November 2009
Detailed analysis of T cell dynamics in humans is challenging and mouse models can be important tools for characterizing T cell dynamic processes. In a paper just published in Journal of Biology, Marques et al. suggest that a mouse model with its activated CD4+ T cells are deleted has relevance for HIV infection.