Coordinated gene expression by post-transcriptional regulons in African trypanosomes
Centre de Recherche en Infectiologie and Département de Microbiologie-Infectiologie et Immunologie, Université Laval, Québec, G1V 4G2, Canada
Journal of Biology 2009, 8:100 doi:10.1186/jbiol203Published: 14 December 2009
The regulation of gene expression in trypanosomes is unique. In the absence of transcriptional control at the level of initiation, a subset of Trypanosoma brucei genes form post-transcriptional regulons in which mRNAs are co-regulated in response to differentiation signals.