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Coordinated gene expression by post-transcriptional regulons in African trypanosomes

Marc Ouellette and Barbara Papadopoulou

Author Affiliations

Centre de Recherche en Infectiologie and Département de Microbiologie-Infectiologie et Immunologie, Université Laval, Québec, G1V 4G2, Canada

Journal of Biology 2009, 8:100  doi:10.1186/jbiol203

Published: 14 December 2009

Abstract

The regulation of gene expression in trypanosomes is unique. In the absence of transcriptional control at the level of initiation, a subset of Trypanosoma brucei genes form post-transcriptional regulons in which mRNAs are co-regulated in response to differentiation signals.

See research articles http://www.biomedcentral.com/1471-2164/10/427 webcite, http://www.biomedcentral.com/1471-2164/10/482 webcite and http://www.biomedcentral.com/1471-2164/10/495 webcite.