Minireview
Scribble at the crossroads
Author affiliations
Institut Pasteur, Cell Polarity and Migration Group and CNRS URA 2582, 25 rue du Dr Roux, 75724 Paris cedex 15, France
Citation and License
Journal of Biology 2009, 8:104 doi:10.1186/jbiol190
Published: 29 December 2009Abstract
Although proteins involved in determining apical-basal cell polarity have been directly linked to tumorigenesis, their precise roles in this process remain unclear. A recent report in BMC Biology clarifies the signaling pathways that control cell polarity, proliferation and apoptosis downstream of the tumor suppressor and apical-basal polarity determinant Scribble.
See research article http://www.biomedcentral.com/1741-7007/7/62 webcite.
