The bacterial pathogen Listeria monocytogenes: an emerging model in prokaryotic transcriptomics

doi:10.1186/jbiol202

Journal of Biology

Volume 8
Issue 12

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The bacterial pathogen Listeria monocytogenes: an emerging model in prokaryotic transcriptomics

Pascale Cossart¹^,2^,3 and Cristel Archambaud¹^,2^,3

¹Institut Pasteur, Unité des Interactions Bactéries Cellules, Paris F-75015, France

²Inserm U604, Paris F-75015, France

³INRA USC2020, Paris F-75015, France

author email corresponding author email

Journal of Biology 2009, 8:107doi:10.1186/jbiol202


Published:	30 December 2009

Abstract

A major challenge in bacterial pathogenesis is understanding the molecular basis of the switch from saprophytism to virulence. Following a recent whole-genome transcriptomic analysis using tiling arrays, an article published in BMC Genomics reports the first use of RNA-seq in Listeria monocytogenes in order to identify genes controlled by sigma B, a transcriptional regulator with a critical role in virulence.

See research article http://biomedcentral.com/1471-2164/10/641 webcite