Distant metastasis: not out of reach any more

doi:10.1186/jbiol128

Journal of Biology

Volume 8
Issue 3

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Distant metastasis: not out of reach any more

François Bertucci¹^,2^,3 and Daniel Birnbaum¹

¹Centre de Recherche en Cancérologie de Marseille, laboratoire d'Oncologie Moléculaire; UMR891 Inserm; Institut Paoli-Calmettes, 13009 Marseille, France

²Département d'Oncologie Médicale, Institut Paoli-Calmettes, 13009 Marseille, France

³Faculté de Médecine, Université de la Méditerranée, Marseille, France

author email corresponding author email

Journal of Biology 2009, 8:28doi:10.1186/jbiol128


Published:	27 March 2009

Abstract

Metastasis is the major cause of death in breast cancer patients. Gene-expression studies have shown that the likelihood of metastasis can be predicted from analysis of primary tumors. Two recent papers in BMC Medicine and BMC Cancer have established new operational expression signatures containing a limited number of genes involved in angiogenesis or cell proliferation.