|
The 27 genes included in the two signatures |
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| Gene symbol |
Gene name |
Hu et al. [3] |
Tutt et al. [4] |
Basal* |
16-kinases† |
GGI‡ |
|
|
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| ADM |
Adrenomedullin |
Yes |
Up |
|||
| ANGPTL4 |
Angiopoietin-like 4 |
Yes |
||||
| C14orf58 |
Chromosome 14 open reading frame 58 |
Yes |
Up |
|||
| DDIT4 |
DNA-damage-inducible transcript 4 |
Yes |
Up |
|||
| FABP5 |
Fatty acid binding protein 5 (psoriasis-associated) |
Yes |
Up |
|||
| GAL |
Galanin |
Yes |
Up |
|||
| NDRG1 |
N-myc downstream regulated gene 1 |
Yes |
Up |
|||
| NP |
Nucleoside phosphorylase |
Yes |
Up |
|||
| PLOD1 |
Procollagen-lysine 1,2-oxoglutarate 5-dioxygenase 1 |
Yes |
Up |
|||
| RRAGD |
Ras-related GTP binding D |
Yes |
Up |
|||
| SLC16A3 |
Solute carrier family 16 (monocarboxylic acid transporters), member 3 |
Yes |
||||
| UCHL1 |
Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
Yes |
Up |
|||
| VEGF |
Vascular endothelial growth factor |
Yes |
Up |
|||
| BUB1 |
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) |
Yes |
Up |
Yes |
Yes |
|
| CCNB1 |
Cyclin B1 |
Yes |
Up |
Yes |
||
| CENPA |
Centromere protein A, 17 kDa |
Yes |
Up |
Yes |
||
| DC13 |
DC13 protein |
Yes |
Yes |
|||
| DIAPH3 |
Diaphanous homolog 3 (Drosophila) |
Yes |
||||
| MELK |
Maternal embryonic leucine zipper kinase |
Yes |
Up |
Yes |
||
| MYBL2 |
v-Myb myeloblastosis viral oncogene homolog (avian)-like 2 |
Yes |
Up |
Yes |
||
| ORC6L |
Origin recognition complex, subunit 6 like (yeast) |
Yes |
Up |
|||
| PKMYT1 |
Protein kinase, membrane associated tyrosine/threonine 1 |
Yes |
Up |
|||
| PRR11 |
Proline rich 11 |
Yes |
||||
| RACGAP1 |
Rac GTPase activating protein 1 |
Yes |
||||
| RFC4 |
Replication factor C (activator 1) 4, 37 kDa |
Yes |
Up |
|||
| TK1 |
Thymidine kinase 1, soluble |
Yes |
||||
| UBE2S |
Ubiquitin-conjugating enzyme E2S |
Yes |
Up |
|||
|
*Genes upregulated in basal versus luminal A tumors [5]; †16-kinase signature [8]; ‡genomic grade index [7]. | ||||||
Bertucci and Birnbaum Journal of Biology 2009 8:28 doi:10.1186/jbiol128 |
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